U.S. Sen Rob Portman announced last month he wouldn’t run again in 2022. He had endorsed Mandel in what was looking to be a crowded primary for the 2018 U.S. Senate race.
Former U.S. Rep. Jim Renacci has also expressed interest in running for U.S. Senate, as he did against Sen. Sherrod Brown in 2018. But he also is apparently considering launching a primary challenge against Gov. Mike DeWine in 2022.
On the Democratic side, Dayton mayor Nan Whaley is considered a leading contender, along with Youngstown-area Congressman Tim Ryan (D-OH 13). Former Ohio Department of Health Director Dr. Amy Acton is also considering a run. Former Columbus mayor Michael Coleman has said he won’t run but will weigh in on the race.